diff --git a/setup.py b/setup.py
--- a/setup.py
+++ b/setup.py
@@ -41,38 +41,38 @@ __platform__ = platform.system()
 is_windows = __platform__ in ['Windows']
 
 requirements = [
-    "alembic >= 1.0.10, < 1.5",
+    "alembic >= 1.0.10, < 1.14",
     "gearbox >= 0.1.0, < 1",
-    "waitress >= 0.8.8, < 1.5",
+    "waitress >= 0.8.8, < 3.1",
     "WebOb >= 1.8, < 1.9",
     "backlash >= 0.1.2, < 1",
     "TurboGears2 >= 2.4, < 2.5",
     "tgext.routes >= 0.2.0, < 1",
     "Beaker >= 1.10.1, < 2",
-    "WebHelpers2 >= 2.0, < 2.1",
-    "FormEncode >= 1.3.1, < 2.1",
+    "WebHelpers2 >= 2.0, < 2.2",
+    "FormEncode >= 1.3.1, < 2.2",
     "SQLAlchemy >= 1.2.9, < 1.4",
-    "Mako >= 0.9.1, < 1.2",
-    "Pygments >= 2.2.0, < 2.7",
+    "Mako >= 0.9.1, < 1.4",
+    "Pygments >= 2.2.0, < 2.8",
     "Whoosh >= 2.7.1, < 2.8",
-    "celery >= 5, < 5.1",
-    "Babel >= 1.3, < 2.9",
-    "python-dateutil >= 2.1.0, < 2.9",
+    "celery >= 5, < 5.5",
+    "Babel >= 1.3, < 2.16",
+    "python-dateutil >= 2.1.0, < 2.10",
     "Markdown >= 2.2.1, < 3.2",
-    "docutils >= 0.11, < 0.17",
+    "docutils >= 0.11, < 0.20",
     "URLObject >= 2.3.4, < 2.5",
-    "Routes >= 2.0, < 2.5",
-    "dulwich >= 0.19.0, < 0.20",
-    "mercurial >= 5.2, < 6.2",
-    "decorator >= 4.2.1, < 4.5",
-    "Paste >= 2.0.3, < 3.5",
-    "bleach >= 3.2, < 4.2",
-    "Click >= 7.0, < 8",
+    "Routes >= 2.0, < 2.6",
+    "dulwich >= 0.19.0, < 0.22",
+    "mercurial >= 5.2, < 6.9",
+    "decorator >= 4.2.1, < 5.2",
+    "Paste >= 2.0.3, < 3.11",
+    "bleach >= 3.2, < 5",
+    "Click >= 7.0, < 8.2",
     "ipaddr >= 2.2.0, < 2.3",
     "paginate >= 0.5, < 0.6",
     "paginate_sqlalchemy >= 0.3.0, < 0.4",
-    "bcrypt >= 3.1.0, < 3.2",
-    "pip >= 20.0, < 999",
+    "bcrypt >= 3.1.0, < 4.2",
+    "pip >= 20.0, < 24.1",
     "chardet >= 3",
 ]
 if sys.version_info < (3, 8):